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Table 1 Effect of EECM on body weight and uterine weight in vivo. *p < 0.01 and **p < 0.001 versus SHAM group: #p < 0.05, ##p < 0.01 and ###p < 0.001 versus OVX group

From: Circaea mollis Siebold & Zucc. Alleviates postmenopausal osteoporosis in a mouse model via the BMP-2/4/Runx2 pathway

GroupSHAMOVXE + PEECM10EECM40
Body weight (g)
Initial17.82 ± 0.4717.81 ± 0.3117.82 ± 0.4117.81 ± 0.4017.82 ± 0.27
Final21.79 ± 0.5824.76 ± 0.38*24.80 ± 1.19*25.34 ± 0.74***25.99 ± 0.86**
Difference of body weight (Final-Initial)3.88 ± 0.497.08 ± 0.53*7.05 ± 0.79*8.17 ± 0.43***7.59 ± .071**
Uterus (mg)56.19 ± 4.8512.59 ± 0.82**24.67 ± 3.44**,###10.46 ± 0.42**11.06 ± 0.46**