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Table 5 Some hematological parametres of rats after 6 months of treatment with the aqueous extract of C. molle

From: Chronic oral safety study of the aqueous extract of Combretum molle twigs on biochemical, haematological and antioxidant parameters of Wistar rats

Parameters

Groups

Control

62.5 mg/kg

125 mg/kg

250 mg/kg

RBC (106/ mm3)

7.37 ± 0.4

8.24 ± 0.30

8.4 ± 0.05

9.42 ± 0.23**

Hb (g/ dL)

12.77 ± 0.09

13.57 ± 0.53

13.53 ± 0.07

15.27 ± 0.31**

HCT (%)

42.7 ± 1.23

43.16 ± 0.47

44.6 ± 0.81

50.00 ± 2.49*

WBC (103/mm3)

4.47 ± 0.14

6.37 ± 0.29**

6.57 ± 0.28**

6.90 ± 0.25***

PLT (103/mm3)

276.00 ± 2,89

303.00 ± 4.17***

323.67 ± 4.17***

340.67 ± 3.84***

MCV (pg)

53.67 ± 0.89

52.14 ± 0.47

52.67 ± 1.46

57.67 ± 0.89

MCH (g/dL)

16.24 ± 0.14

16.34 ± 0.03

16.24 ± 0.30

16.43 ± 0.12

MCCH (g/dL)

29.50 ± 0.38

30.97 ± 0.38

31.00 ± 1.05

29.23 ± 0.96

MPV (fL)

11.03 ± 0.08

10.57 ± 0.21

8.77 ± 0.12

9.70 ± 0.17

Lymphocytes (%)

45.77 ± 0.27

50.17 ± 2.10

48.3 ± 1.20

47.63 ± 1.16

Monocytes (%)

10.90 ± 0.05

11.97 ± 0.24

11.00 ± 0.30

11.16 ± 0.59

Granulocytes (%)

27.87 ± 0.29

29.14 ± 1.01

27.30 ± 0.35

28.37 ± 1.21

  1. Values are expressed as mean ± SD, n = 10. (One-way ANOVA followed by Turkey’s post-hoc test). *P < 0.05; **P < 0.01; ***P < 0.001 significantly different when compared to the control group