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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Iridoid glycosides from Morinda officinalis How. exert anti-inflammatory and anti-arthritic effects through inactivating MAPK and NF-κB signaling pathways

Fig. 6

Effects of MOIG on the histopathological characteristics of joint and synovial tissue in CFA -induced arthritic rats (HE, × 200). CFA -induced arthritic rats exhibited severe synovial hyperplasia, infiltration of inflammatory cells, and pannus formation, which severely lead to cartilage hyperplasia and erosion. TGs, MTX, MO and MOIG reversed these pathological alterations in joint and synovial tissue of CFA -induced arthritic rats. Note: Normal control, normal non-arthritic rats; Model control, arthritic non treated rats; TGs, Rats with arthritic and treated with TGs; MTX, Rats with arthritic and treated with MTX; MO, Rats with arthritic and treated with MO; MOIG-25 mg/kg, Rats with arthritic and treated with MOIG at dose of 25 mg/kg; MOIG-50 mg/kg, Rats with arthritic and treated with MOIG at dose of 50 mg/kg; MOIG-100 mg/kg, Rats with arthritic and treated with MOIG at dose of 100 mg/kg

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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