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Table 4 Effect of PPE in the early (0-5 min) and late phases (15-30 min) of the formalin test in mice

From: A mechanistic approach to HPLC analysis, antinociceptive, anti-inflammatory and postoperative analgesic activities of panch phoron in mice

TreatmentDoseLicking Time (sec)% of inhibition
0–5 min15–30 min0–5 min15–30 min
Control (distilled water)10 ml/kg18 ± 1.616.4 ± 1.03  
Na diclofenac10 mg/kg8.4 ± 0.51*1.8 ± 0.37*52.872.3
PPE100 mg/kg10.8 ± 0.86*1.6 ± 0.24*40.073.8
PPE250 mg/kg8.0 ± 0.32*1.6 ± 0.24*54.475.4
PPE500 mg/kg6.2 ± 0.37*1.2 ± 0.20*65.080.0
  1. N = 6. Values are mean ± SEM. *p < 0.05 compared to control (Repeated measures ANOVA followed by Dunnett’s post hoc test)