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Table 6 One Month Study Blood Chemistry Control and 2014HP group by Sex ANOVA (bold – significant differences)

From: Toxicology studies of aqueous-alcohol extracts of Harpagophytum procumbens subsp. procumbens (Burch.) DC.Ex Meisn. (Pedaliaceae) in female and male rats

Serum measureGROUP main effectSEX main effectGROUP X SEX interactionSpecial Notes *Report as p < .001
 F, p value (df 1,19)F, p value (df 1, 19)F, p value (df 1, 19) 
Glucose (mg/dL)6.27, .025.47, .030.89, .36Placebo > 2014 HP & Females < Males
Urea Nitrogen (mg/dL)0.04, .84.12, .742.03, .17No significant interaction
Creatinine (mg/dL)0.13, .7324.89, <.0010.29, .60Females > Males
Sodium (mEq/L)2.07, .170.01, .932.65, .12No significant interaction
Potassium (mEq/L)27.70, <.00125.14, <.00129.88, <.001differences between the groups is different for females and males.
Females: Placebo > 2014 HP Males: Placebo < 2014 HP**
Chloride (mEq/L)0.07, .807.98, .010.03, .87Females > Males
Bicarbonate (mEq/L)0.90, .3618.27, <.0016.95, .02differences between the groups is different for females and males.
Females: Placebo < 2014 HP Males: Placebo > 2014 HP
Anion Gap (mEq/L)18.69, <.0010.23, .642.83, .11Placebo < 2014 HP
Albumin (g/dL)0.17, .6977.95, <.0010.51, .49Females > Males
Total Protein (g/dL)1.42, .2574.89, <.0010.26, .62Females > Males
Globulin (g/dL)6.40, .0216.81, .0010.03, .87Placebo > 2014 HP** & Females > Males
Calcium (mg/dL)0.11, .7445.25, <.0010.91, .35Females > Males
Phosphorus (mg/dL)9.82, .00514.87, .0010.61, .45Placebo < 2014 HP & Females < Males
Cholesterol (mg/dL)0.02, .9011.89, .0030.08, .78Females < Males
Total Bilirubin (mg/dL)66.58, <.0014.29, .0524.29, .052Placebo < 2014 HP**
ALT (U/L)0.65, .4321.51, <.0010.20, .66Females < Males
ALP (U/L)1.04, .328.09, .013.00, .10Females < Males
GGT (U/L)All values were “< 3” – no analyses conducted 
CK (U/L)4.36, .056.75, .028.28, .01differences between the groups is different for females and males.
Females: Placebo < 2014 HP Males: Placebo > 2014 HP
Hemolysis (Mild to moderate hemolysis may cause false increases in direct bilirubin and AST measurement. Marked hemolysis can adversely affect all chemistry tests.)Overall Model Test - X2 = 9.04, df 3, p = .03
Binary logistic regression to predict hemolysis. Wald X2 statistic
 
 X2 = 0.11, df 1, p = .74X2 = 0.0, df 1, p = .99X2 = 0.0, df 1, p = 1.0 
  1. **HP group(s) was significantly (p < .05) different from Control Group