Fig. 1
From: The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines
The effect of AELE on cell proliferation using MTS assay. Proliferation of Monomac-1(a) and KG-1 (b) cells after 24, 48, and 72 h of treatment with increasing concentrations of AELE. The absorbance was measured at 492 nm. A significant dose and time-dependent decrease in proliferation of AML cells was observed upon increasing concentrations of AELE. The IC50 s were reached at 333.4 μg/mL for Monomac-1 and 254.5 μg/mL for KG-1 at 24 h. A time-dependent decrease in the IC50 s was observed for both cell lines at 48 and 72 h. (* indicates a p-value: 0.01 < p < 0.05, ** indicates a p- value: 0.001 < p < 0.01, and **** indicates a p-value: p < 0.0001)