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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

Fig. 4

Alterations of prefrontal cortical neurons induced by CUMS as well as XYS and Flu treatment were measured using hematoxylin-eosin staining a and Nissl staining. b Demonstrating pathologic changes and neuronal morphology of the PrL region of PFC. The micrographs in the first row were captured using a low-magnification microscope (scale bar = 100 μm, 100× magnification); the remaining micrographs were captured using a higher-magnification microscope (scale bar = 20 μm, 400× magnification). c. Quantitative analysis of the neuron numbers of Nissl-stained neurons in the PFC PrL region. The Nemenyi method is used for data comparative analysis between groups. Values are presented as the medians and interquartile ranges, (n = 5), **P < 0.01 versus the control group; #P < 0.05, ##P < 0.01 versus the CUMS group

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