Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 The MIC (μg/ml) of CG sub-fractions, synthetic and commercially sourced gallate derivatives against a panel of six bacteria

From: Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis

Fractions/pure compound S. aureus S. epidermidis E. coli B. subtilis B. cereus A. faecalis
CGEEA-F5 256 128 1024 >  1024 1024 256
CGEEA-F5–8 128 64 512 NA NA 128
3,4,5-Trihydroxybenzoic acid (gallic acid, 1) 2000 500 1000 1000 1000 1000
3,4-Dihydroxybenzoic acid (2) 1000 500 1000 1000 1000 500
4-Hydroxy-3-methoxybenzoic acid (3) 1000 1000 1000 1000 1000 500
4-Hydroxy-3,5-dimethoxybenzoic acid (4) 1000 1000 500 1000 2000 500
3,4,5- Trimethoxybenzoic acid (5) 1000 1000 1000 1000 1000 500
Ethyl 3,4,5-trihydroxybenzoate (ethyl gallate, 6) 1000 250 62.5 1000 1000 250
Propyl 3,4,5-trihydroxybenzoate (7) 500 250 125 1000 1000 250
Propan-2-yl 3,4,5-trihydroxybenzoate (8) 1000 250 62.5 >1000 >1000 250
2-Methylpropyl 3,4,5-trihydroxybenzoate (9) 500 250 500 1000 1000 500
2-Methylbutyl 3,4,5-trihydroxybenzoate (10) 250 250 250 250 500 250
3-Methylbutyl 3, 4, 5-trihydroxybenzoate (11) 250 250 250 250 500 500
3-Methylbut-2-en-1-yl 3,4, 5-trihydroxybenzoate (12) 250 250 500 500 1000 500
Dodecyl 3,4,5-trihydroxybenzoate (lauryl gallate, 13) 8 8 >1000 31.25 31.25 1000
Ampicillin ≤0.5 ≤0.5 ≤0.5 ≤0.5 >64 16
  1. NA not assayed