Fig. 5

Activity of POL-P3b-induced protection of intestinal DC from cervical cancer-induced apoptosis involved in PI3K/AKT and NF-κB signaling pathway a Western blot analysis showing the levels of phosphorylated p38, ERK, JNK and AKT in intestinal DC. b The PI3K downstream target was analyzied. Intestinal DC isolated from mice treated with or without POL-P3b were pretreated by LY294002 (60 μmol/L) for 1.5 h. The Akt activity, the NF-κB activation and the expression of Bcl-2 in intestinal DC was suppressed by the pretreatment of LY294002