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Table 2 Effect of the studied plant extracts and Ketosteril (Ks) on the viability of the untreated Vero cells and their effective doses (ED100) that produced 100% therapeutic response from the carbon tetrachloride (CCl4)-induced nephrotoxicity

From: In vitro anti-nephrotoxic potential of Ammi visnaga, Petroselinum crispum, Hordeum vulgare, and Cymbopogon schoenanthus seed or leaf extracts by suppressing the necrotic mediators, oxidative stress and inflammation

  Ammi visnaga extract (AVE) Petroselinum crispum extract (PCE) Hordeum vulgare extract (HVE) Cymbopogon schoenanthus extract (CSE) Ks
EC100 (μg/ml) 999.48 ± 49.05 d 2209.87 ± 23.96 b 2709.07 ± 18.20 a 1371.75 ± 7.65 c 450.74 ± 1.31 e
IC50 (μg/ml) 6334.53 ± 86.20 a 9023.38 ± 46.36 b 9024.16 ± 611.32 b 11,725.59 ± 13.40 c 12,785.56 ± 1.24 d
ED100 (μg/ml) 83.64 ± 3.06 a 140.71 ± 1.78 b 174.77 ± 2.06 cd 148.10 ± 14.42 bc 189.05 ± 5.74 d
  1. Results are presented as Mean ± SE (n = 3). Different letters in the same row are significantly different at p < 0.05. EC100, safe concentrations of the studied extracts that caused 100% viability for Vero cells; IC50, concentration of the studied extracts that caused 50% viability for Vero cells