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Table 3 Cytotoxicity against Vero cells LC50 (μg/ml) and Selectivity index of the nine selected acetone crude extracts. Selectivity index values more than 1 are non-toxic extracts with a relatively good safe margin and promising antibacterial agents

From: Antibacterial and antibiofilm activity of acetone leaf extracts of nine under-investigated south African Eugenia and Syzygium (Myrtaceae) species and their selectivity indices

 

Selectivity index

Cytotoxicity

E. faecalis

B. cereus

S. aureus

E. coli

P. aeruginosa

S. typhimurium

Average

E. erythrophylla

250 ± 0.06

0.78

12.55

3.14

2.35

1.57

0.78

3.53

E. natalitia

38 ± 0.01

0.48

0.48

0.24

0.24

0.48

0.24

0.36

E. woodii

202 ± 0.001

0.32

1.29

2.59

1.29

1.29

2.59

1.56

E. umtamvunensis

820 ± 0.05

5.27

21.07

10.54

2.63

5.27

2.63

7.90

E. zeyheri

1140 ± 0.17

0.91

14.53

14.53

8.72

3.63

7.27

8.27

S. legatii

140 ± 0.05

1.74

4.18

1.74

1.74

1.74

3.48

2.44

S. masukuense

70 ± 0.01

1.87

0.94

0.47

0.94

0.94

0.94

1.02

S. species A

61 ± 0.004

1.57

0.39

1.57

0.79

0.79

1.57

1.11

S. gerrardii

200 ± 0.03

5.11

1.28

2.56

0.64

1.28

5.11

2.66

Doxorubicin

12.07 ± 0.41

ND

ND

ND

ND

ND

ND

ND