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Table 1 Key safety criteria adapted from monographs developed by the National Center for Complementary and Integrative Health (NCCIH)

From: What has been the impact of the Traditional Herbal Registration (THR) scheme in the UK on information provided with herbal products bought over the counter?

Herbal product

Precautions

Interactions

Side effects

St John’s Wort

Increased sensitivity to sunlight

Antidepressants

Birth control pills

Cyclosporin, which prevents the body from rejecting transplanted organs

Digoxin, a heart medication

Some HIV drugs including indinavir

Some cancer medications including irinotecan

Warfarin, an anticoagulant

Taking ST John’s Wort with certain antidepressants or other drugs that affect serotonin may lead to increased serotonin-related side effects which may be potentially serious

Anxiety

Dry mouth

Dizziness

GI symptoms

Fatigue

Headache

Sexual dysfunction

Ginkgo

If you are older, have a known bleeding risk, or are pregnant you should be cautious about gingko possibly increasing your risk of bleeding

Anticoagulants

Headache

Stomach upset

Allergic skin reactions

Ginseng (Asian)

Some evidence suggests that ginseng might affect blood sugar and blood pressure. If you have diabetes or high blood pressure consult your healthcare provider before using Asian ginseng

Pregnancy and breastfeeding?

warfarin

Headaches

Sleep problems

Digestive problems

Garlic

Taking garlic may increase the risk of bleeding. If you take an anticoagulant such as warfarin or if you need surgery tell your healthcare provider if you’re taking or planning to take garlic dietary supplements

Warfarin

Saquinavir (HIV)

Breath and body odour

Heartburn

Upset stomach

Some people have allergic reactions to garlic

Echinacea

Some people have allergic reactions which might be rare

People with atopy may be more likely to have an allergic reaction when taking Echinacea

 

Digestive tract symptoms such as nausea or stomach pain