Fig. 2

Inhibitory effects of DS, SQ and DS-SQ 6:4 on elevated levels of LDH leakage in EA.hy926 cells under cellular damage induced by Hcy-Ado-TNF. a. Inhibitory activity (% relative to control) of DS, SQ and DS-SQ 6:4 (10–300 μg/mL) on increased LDH activity (relative to control). Data shown are mean ± SEM, n > 3. b. Concentration-effect curves of LDH inhibitory activity of DS, SQ and DS-SQ 6:4 generated by CompuSyn software. c. Log (CI) values were plotted as a function of suppressing LDH leakage (Fa) by ‘CompuSyn’ software. Dotted line is the reference line, where Log (CI) value equals to 0; solid line represents CI values at different Fa. Fa values correspond to % LDH inhibitory effect relative to control