Fig. 4
From: Wu-Mei-wan protects pancreatic β cells by inhibiting NLRP3 Inflammasome activation in diabetic mice
Effect of WMW on the expression of proteins related to apoptosis in the mouse pancreas. Western blot analyses were (a) caspase-12 and (b) Bcl-2. Band densities were converted to a bar graph. Immunofluorescence staining for insulin (red) and caspase-12 (green) or Bcl-2 (green) in pancreatic islets from wild-type, db/db, and db/db mice treated with HWMW are illustrated in (c) or (d). Nuclei were counterstained with DAPI (blue). Signals for caspase-12 and Bcl-2 were calculated in the bar graph (e, f). Scale: 25 μm. P < 0.05 (*), P < 0.01 (**) (n = 6)