Fig. 5From: 2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cellsThe analysis of cell apoptosis and cell cycle distribution of HCC CSCs induced by 2-ethoxystypandrone (1). a. 2-Ethoxystypandrone (1) induced cell apoptosis of HCC CSCs in dose-dependent manner. Apoptosis rates of HCC CSCs after being treated with 2-ethoxystypandrone (1) at the indicated concentration for 24 h. b. The cell cycle distribution of HCC CSCs after being treated with 2-ethoxystypandrone (1) at the concentration of 10 μM for 24 h. Values are means+SEM, *p < 0.05 and ***p < 0.001, compared to control group. Two-tailed unpaired T-Test was used for statistical analysis by SPSS 19.0 softwareBack to article page