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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

Fig. 4

Apoptosis induction (%) in MCF-7 cells after 5 days treatment with endoxifen in combination with VAEM. Mean values (±SE) of (a) early apoptosis in the presence of 0.5 μM β-estradiol (E2) (b) late apoptosis/necrosis in the presence of 0.5 μM β-estradiol, (c) early apoptosis in the absence of 0.5 μM β-estradiol and (d) late apoptosis/necrosis in the absence of 0.5 μM β-estradiol are presented (*p < 0.05, **p < 0.01, ***p < 0.001)

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