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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

Fig. 3

Apoptosis induction (%) in MCF-7 cells by endoxifen and VAEM, respectively. Mean values (±SE) of early apoptosis, late apoptosis/necrosis and viable cells after 5 days treatment with (a) VAEM in the presence of 0.5 μM β-estradiol (E2), (b) endoxifen in the presence of 0.5 μM β-estradiol, (c) VAEM in the absence of 0.5 μM β-estradiol and (d) endoxifen in the absence of 0.5 μM β-estradiol are presented. Significance values are given relative to the untreated control (*p < 0.05, **p < 0.01, ***p < 0.001)

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