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Table 3 Inhibition zone (mm) of combined essential oils against MDR bacteria at AAU, 2018

From: Combined antibacterial effect of essential oils from three most commonly used Ethiopian traditional medicinal plants on multidrug resistant bacteria

TMP μl/disc Gram positive Gram negative
S.aureus E.coli K. pneumoniae
ATCC MRSA ATCC MDR ATCC MDR
T. schimper + B.cuspidata (1:1 ratio) 5 19 ± 1.0 18 ± 1.2 20 ± 1.0 21 ± 0.1 27 ± 1.0 27 ± 0.8#
10 29 ± 1.2 29 ± 0.5** 23 ± 1.2 25 ± 0.1¥ 29 ± 1.2 28 ± 0.3#
15 33 ± 0.1 33 ± 0.6** 28 ± 0.1 26 ± 0.5¥ 33 ± 0.7 34 ± 0.1##
20 38 ± 0.3 39 ± 0.8*** 29 ± 0.1 29 ± 0.8¥¥ 35 ± 1.4 35 ± 0.5##
B. cuspidata + B. ogadensis (1:1 ratio) 5 20 ± 0.4 20 ± 0.1 16 ± 0.4 15 ± 0.9 19 ± 0.7 15 ± 0.4
10 25 ± 0.5 26 ± 0.3* 18 ± 0.6 23 ± 0.2 24 ± 0.4 23 ± 0.2
15 28 ± 0.3 27 ± 0.3** 24 ± 0.5 26 ± 0.4¥ 27 ± 1.2 26 ± 0.4#
20 32 ± 0.1 32 ± 0.1*** 26 ± 0.8 27 ± 0.1¥ 29 ± 0.1 29 ± 0.2##
B. ogadensis + T. schimper (1:1 ratio) 5 11 ± 0.6 11 ± 0.3 9 ± 0.1 10 ± 0.1 12 ± 0.4 12 ± 0.4
10 14 ± 0.3 15 ± 0.7 13 ± 0.8 13 ± 0.8 15 ± 0.6 16 ± 0.6
15 16 ± 0.4 16 ± 0.1 15 ± 0.5 14 ± 0.4 19 ± 0.7 20 ± 0.7
20 19 ± 0.1 19 ± 0.8 17 ± 0.7 21 ± 0.3 21 ± 0.2 20 ± 0.7
Modern drug 24 ± 0.8 11 ± 1.3(R) 22 ± 0.4 17 ± 0.4(R) 23 ± 0.7 17 ± 0.2(R)
  1. The values represent mean ± standard deviation, N NO inhibition zone, R Resistant (≤16 mm IZ), S=Susceptible (≥ 21 mm IZ). Where, *P < 0.05, **P < 0.01, ***P < 0.001when compared to cefoxitin treated MRSA. While, #P < 0.05, ##P < 0.01when compared to modern drug treated K. pneumoniae and ¥ P < 0.05, ¥¥P < 0.01 when compared to modern drug treated E. coli