In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb, Warburgia salutaris (Bertol. F.) Chiov and Curtisia dentata (Burm. F.) C.A.Sm - medicinal plants used in South Africa

Table 4 Cytotoxicity activity of methanol, Acetone and Ethyl Acetate of plant extracts

	Centella asiatica				Curtisia dentata				Warburgia salutaris				Control
Cells	Methanol	Ethyl Acetate	Acetone	water	Methanol	Ethyl Acetate	Acetone	water	Methanol	Ethyl Acetate	Acetone	water	Dox
MCF-7	77.6 ± 0.12	49.36 ± 0.04	53.65 ± 0.06	> 100	82.6 ± 0.13	61.38 ± 0.05	43.24 ± 0.01	76.7 ± 0.04	59.57 ± 1.23	44.59 ± 0.70	34.15 ± 0.77	> 100	1.26 ± 0.03
CACO-2	> 100	> 100	81.88 ± 1.35	> 100	78.56 ± 0.31	74.71 ± 1.25	57.35 ± 0.04	> 100	> 100	92.23 ± 0.15	73.29 ± 0.16	> 100	2.76 ± 0.06
HELA	78.30 ± 1.60	74.75 ± 0.24	56. 88 ± 0.72	76.3 ± 0.06	61. 30 ± 0.33	59.49 ± 0.04	45.13 ± 0.03	98.7 ± 1.25	84. 00 ± 1.25	71.27 ± 0.09	56. 01 ± 0.38	77.5 ± 0.11	1.43 ± 0.24
A549	68.51 ± 0.25	63.73 ± 0.16	46.49 ± 0.04	> 100	67.35 ± 0.33	53.27 ± 0.76	41.55 ± 0.04	> 100	52.51 ± 0.24	56.72 ± 1.92	44.51 ± 1.25	> 100	2.10 ± 0.11

IC₅₀ values of the Cytotoxicity of plant extracts on different cancer cell lines MCF-7, CACO-2, HeLa and A549. DOX = Doxorubicin hydrochloride. Data expressed as mean ± standard deviation, n = 3. (P ≤ 0.05)

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