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Table 1 Antibacterial activities of Leaf extracts of Centella asiatica, Warburgia salutaris and Curtisia dentate

From: In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb, Warburgia salutaris (Bertol. F.) Chiov and Curtisia dentata (Burm. F.) C.A.Sm - medicinal plants used in South Africa

Zone 0f inhibition

 

Centella

Asiatica

Curtisia

Dentate

Warburgia

salutaris

Controls

Test organisms

Methanol

Ethyl

Acetate

Acetone

water

Methanol

Ethyl

Acetate

Acetone

water

Methanol

Ethyl

Acetate

Acetone

water

Cipro

1% DMSO

E. avium

19 ± 2.0

12 ± 0.4

13 ± 2.0

10 ± 0.4

18 ± 1.5

11 ± 2.0

15 ± 0.6

7 ± 0.1

16 ± 0.6

11 ± 2.1

14 ± 3.0

11 ± 1.1

31 ± 2.1

NA

S. aureus

18 ± 1.4

13 ± 1.4

10 ± 0.7

7 ± 3.0

15 ± 2.5

13 ± 1.5

17 ± 1.0

11 ± 1.1

19 ± 2.0

12 ± 2.0

21 ± 1.0

8 ± 1.2

27 ± 0.5

NA

S. agalactiae

29 ± 0.4

10 ± 2.5

15 ± 0.3

8 ± 1.2

12 ± 1.5

15 ± 1.2

16 ± 1.5

11 ± 0.2

13 ± 1.2

9 ± 1.2

14 ± 0.5

NA

22 ± 1.5

NA

B. cereus

19 ± 0.0

10 ± 0.4

9 ± 1.2

8 ± 0.6

19 ± 1.5

13 ± 0.6

13 ± 1.0

10 ± 0.8

13 ± 1.2

10 ± 0.6

15 ± 1.0

9 ± .0.9

25 ± 0.5

NA

E. hirae

15 ± 1.0

13 ± 0.4

11 ± 1.4

8 ± 2.8

13 ± 0.7

15 ± 2.5

14 ± 1.2

9 ± 1.5

17 ± 1.5

12 ± 0.8

11 ± 0.5

7 ± 1.5

28 ± 1.5

NA

E. faecalis

16 ± 0.4

21 ± 0.4

13 ± 2.2

10 ± 3.1

18 ± 1.5

13 ± 1.2

14 ± 1.5

11 ± 0.2

12 ± 2.1

10 ± 0.5

12 ± 0.2

8 ± 0.6

35 ± 1.7

NA

E. gallinarium

10 ± 0.5

14 ± 1.7

11 ± 1.0

7 ± 0.3

16 ± 2.0

12 ± 1.2

12 ± 1.0

7 ± 1.4

13 ± 0.6

12 ± 0.3

10 ± 1.0

NA

26 ± 2.0

NA

E. coli

16 ± 0.0

8 ± 1.0

10 ± 0.3

8 ± 1.1

10 ± 1.4

11 ± 1.4

11 ± 1.5

NA

12 ± 1.0

10 ± 1.2

14 ± 1.5

10 ± 1.4

21 ± 1.7

NA

P. aeruginosa

17 ± 1.0

8 ± 0.6

12 ± 1.0

NA

12 ± 0.7

12 ± 0.6

12 ± 1.0

NA

14 ± 1.0

9 ± 1.5

12 ± 0.6

8 ± 1.0

23 ± 1.5

NA

P. mirabilis

14 ± 1.0

10 ± 1.6

9 ± 1.1

8 ± 0.0

10 ± 1.4

15 ± 0.4

15 ± 0.5

9 ± 2.5

16 ± 0.6

NA

11 ± 0.7

NA

26 ± 1.1

NA

P. vulgaris

9 ± 1.0

9 ± 0.6

12 ± 0.6

9 ± 0.8

16 ± 2.5

14 ± 0.3

11 ± 0.8

7 ± 3.0

11 ± 0.0

9 ± 0.6

8 ± 0.4

NA

24 ± 0.5

NA

K. pneumonia

12 ± 2.0

7 ± 0.6

10 ± 0.6

NA

10 ± 2.1

11 ± 1.5

10 ± 1.5

NA

12 ± 1.0

11 ± 2.0

11 ± 1.0

NA

25 ± 2.0

NA

Acinetobacter

Calcaoceuticals

Anitratus

10 ± 0.6

8 ± 0.3

9 ± 0.7

NA

12 ± 2.3

11 ± 1.1

10 ± 0.6

8.0 ± 1.4

13 ± 1.0

10 ± 1.2

10 ± 1.1

NA

23 ± 1.5

NA

S. typhi

11 ± 1.1

9 ± 0.6

7 ± 0.6

NA

12 ± 0.7

10 ± 1.5

12 ± 0.6

NA

13 ± 1.5

11 ± 1.5

9 ± 1.2

NA

27 ± 0.5

NA

  1. Inhibition zone diameters (mm) including diameter of the sterile disc (6 mm): values are given as mean ± SD (3 replicates). ND = not determined; NA = not active. DMSO = Dimethyl sulfoxide. SD = standard deviation. (P ≤ 0.05)