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Table 3 Bone femur strength, and mineral content (Ca and IP) in sham-operated and OVX mice

From: Anti-osteoporotic effects of mixed compositions of extracellular polymers isolated from Aureobasidium pullulans and Textoria morbifera in ovariectomized mice

Items
Groups
Bone Mineral Density (g/cm2) Strength (Newton) Right femur bone mineral contents
Total body Right femur Right femur Ca (mg/g bone) IP (mg/g bone) Ca/IP ratio
Controls
 Sham 0.0249 ± 0.0007 0.0274 ± 0.0008 12.47 ± 1.66 59.08 ± 10.25 45.42 ± 7.57 1.30 ± 0.07
 OVX 0.0215 ± 0.0003f 0.0231 ± 0.0001a 6.69 ± 0.91f 33.37 ± 3.32f 26.14 ± 3.26f 1.28 ± 0.11
RES 2.5 mg/kg 0.0251 ± 0.0008h 0.0262 ± 0.0013bc 11.27 ± 1.78h 55.33 ± 11.04h 44.03 ± 10.17h 1.26 ± 0.05
EAP 200 mg/kg 0.0233 ± 0.0003fh 0.0252 ± 0.0007ac 8.59 ± 0.63fh 42.76 ± 4.14fh 33.27 ± 3.18fh 1.29 ± 0.06
TM 200 mg/kg 0.0231 ± 0.0004fh 0.0248 ± 0.0006ac 7.96 ± 0.69fi 39.28 ± 3.84fi 31.32 ± 3.51fh 1.26 ± 0.06
Mixed formula - EAP:TM (200 mg/kg)
 1:1 0.0333 ± 0.0003fh 0.0253 ± 0.0006ac 8.32 ± 0.98fh 40.63 ± 2.92fh 31.79 ± 2.93fh 1.28 ± 0.07
 1:3 0.0232 ± 0.0003fh 0.0253 ± 0.0008ac 8.04 ± 0.67fi 40.77 ± 3.43fi 32.39 ± 3.40fi 1.26 ± 0.06
 1:5 0.0231 ± 0.0003fh 0.0250 ± 0.0010ac 8.23 ± 0.86fh 41.48 ± 4.10fh 32.85 ± 3.64fh 1.27 ± 0.09
 1:7 0.0232 ± 0.0004fh 0.0252 ± 0.0009ac 8.08 ± 0.88fh 40.39 ± 1.58fh 31.51 ± 1.58fh 1.28 ± 0.04
 1:9 0.0232 ± 0.0003fh 0.0249 ± 0.0008ac 8.29 ± 0.84fi 40.35 ± 4.00fi 32.17 ± 3.02fi 1.25 ± 0.05
 3:1 0.0244 ± 0.0005hjl 0.0268 ± 0.0011cde 10.58 ± 1.17ghjl 48.96 ± 2.87hhjl 38.25 ± 2.96ghkl 1.28 ± 0.06
 5:1 0.0234 ± 0.0006fh 0.0256 ± 0.0015ac 8.48 ± 0.81fh 42.67 ± 5.16fh 33.66 ± 4.52fh 1.27 ± 0.06
 7:1 0.0232 ± 0.0004fh 0.0249 ± 0.0010ac 8.36 ± 0.54fh 42.25 ± 3.11fh 33.26 ± 3.28fh 1.28 ± 0.09
 9:1 0.0232 ± 0.0003fh 0.0250 ± 0.0005ac 8.45 ± 0.69fh 40.21 ± 3.74fh 31.61 ± 2.00fh 1.27 ± 0.05
  1. OVX Bilateral ovariectomy, RES Risedronate sodium, EAP Exopolymers purified from A. pullulans SM2001, TM T. morbifera leaf extracts, (EAP:TM) Mixed formula consisted of EAP and TM (g/g), Ca Calcium, IP Inorganic phosphorus
  2. Values are expressed mean ± S.D. of eight mice
  3. ap < 0.01 and bp < 0.05 as compared with sham control by LSD test
  4. dp < 0.01 as compared with EAP single formula treated mice by LSD test
  5. cp < 0.01 as compared with OVX control by LSD test
  6. ep < 0.01 as compared with TM single formula treated mice by LSD test
  7. fp < 0.01 and gp < 0.05 as compared with sham control by MW test
  8. jp < 0.01 and kp < 0.05 as compared with EAP single formula treated mice by MW test
  9. hp < 0.01 and ip < 0.05 as compared with OVX control by MW test
  10. lp < 0.01 as compared with TM single formula treated mice by MW test