Skip to main content

Table 1 In vitro cytotoxicity of different extracts and fractions of B. rupestris and B. discolor against HepG2, MDA-MB-231 and A549 cell lines

From: Study of the anti-allergic and anti-inflammatory activity of Brachychiton rupestris and Brachychiton discolor leaves (Malvaceae) using in vitro models

Cell line BRT BRH BRD BRE BRR BDT BDH BDD BDE doxorubicin
HepG2 1.28 −2.078 −8.02 −8.43 −13.74 1.66 −7.43 −16.18 −6.62 91.28 ± 0.3
MDA-MB-231 −15.86 − 9.70 −18.83 −25.52 − 23.30 − 6.19 − 6.73 13.17 −20.64 97.69 ± 0.4
A549 0.44 −0.81 7.85 −8.37 −0.89 12.59 8.18 14.99 −6.52 98.05 ± 0.0
  1. Results are presented as growth inhibition percentage at concentration of 20 μg/mL, mean (n = 1). Doxorubicin (2 μg/mL) was used as the reference drug, mean ± SD (n = 2). BRT: B. rupestris total methanol extract; BHT: B. rupestris n-hexane fraction; BRD: B. rupestris dichloromethane fraction; BRE: B. rupestris ethyl acetate fraction; BRR: B. rupestris remaining MeOH(aq) fraction; BDT: B. discolor total methanol extract; BDH: B. discolor n-hexane fraction; BDD: B. discolor dichloromethane fraction; BDE: B. discolor ethyl acetate fraction