Cell line
|
BRT
|
BRH
|
BRD
|
BRE
|
BRR
|
BDT
|
BDH
|
BDD
|
BDE
|
doxorubicin
|
---|
HepG2
|
1.28
|
−2.078
|
−8.02
|
−8.43
|
−13.74
|
1.66
|
−7.43
|
−16.18
|
−6.62
|
91.28 ± 0.3
|
MDA-MB-231
|
−15.86
|
− 9.70
|
−18.83
|
−25.52
|
− 23.30
|
− 6.19
|
− 6.73
|
13.17
|
−20.64
|
97.69 ± 0.4
|
A549
|
0.44
|
−0.81
|
7.85
|
−8.37
|
−0.89
|
12.59
|
8.18
|
14.99
|
−6.52
|
98.05 ± 0.0
|
- Results are presented as growth inhibition percentage at concentration of 20 μg/mL, mean (n = 1). Doxorubicin (2 μg/mL) was used as the reference drug, mean ± SD (n = 2). BRT: B. rupestris total methanol extract; BHT: B. rupestris n-hexane fraction; BRD: B. rupestris dichloromethane fraction; BRE: B. rupestris ethyl acetate fraction; BRR: B. rupestris remaining MeOH(aq) fraction; BDT: B. discolor total methanol extract; BDH: B. discolor n-hexane fraction; BDD: B. discolor dichloromethane fraction; BDE: B. discolor ethyl acetate fraction