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Table 2 Effect of MECN on open field test

From: The leaves of Crataeva nurvala Buch-Ham. modulate locomotor and anxiety behaviors possibly through GABAergic system

Treatment Dose (mg/kg) Number of square crossed (% of Inhibition)
Pretreatment 30 min 60 min 90 min 120 min
Control 0.1 ml/mouse 103.80 ± 3.51 94.40 ± 4.31 83.20 ± 3.09 74.60 ± 3.20 66.80 ± 2.58
Diazepam 1 101.60 ± 3.89 49.20 ± 2.13*** (47.88) 33.20 ± 1.88*** (60.10) 14.80 ± 1.28*** (80.16) 5.40 ± 1.12*** (91.92)
MECN 50 98.00 ± 2.83 67.40 ± 3.79*** (28.60) 42.00 ± 2.49*** (49.52) 31.60 ± 2.87*** (57.64) 16.20 ± 2.40*** (75.75)
MECN 100 100.80 ± 2.62 46.40 ± 2.75*** (50.85) 35.80 ± 2.48*** (56.97) 16.20 ± 4.53*** (78.28) 5.60 ± 0.75*** (91.62)
MECN 200 102.20 ± 3.44 34.40 ± 3.23*** (63.56) 22.20 ± 3.88*** (73.32) 10.80 ± 2.89*** (85.52) 4.20 ± 0.58*** (93.71)
  1. Effect of MECN on open field test. Values are presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; ***p < 0.001 compared with the control group (two-way ANOVA followed by Bonferroni’s test)