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Table 2 Effect of oral treatment of Sida pilosa aqueous extract on plasma total proteins and transaminases activities of Schistosoma mansoni-infected mice

From: Efficacy of Sida pilosa Retz aqueous extract against Schistosoma mansoni – induced granulomatous inflammation in the liver and the intestine of mice: histomorphometry and gastrointestinal motility evaluation

Groups Total proteins ALT AST
Concentration (mg/mL) % change Activity (UI/L) % change Activity (UI/L) % change
UIC 0.91 ± 0.03   116.33 ± 14.28   113.59 ± 9.29  
IC 0.79 ± 0.02* - 13.19 842.60 ± 91.12*** +  624.32 267.81 ± 16.34*** +  135.77
PZQ 0.77 ± 0.03* / 171.64 ± 15.69### - 79.63 179.78 ± 10.58**, ### - 32.87
SpAE 200 0.90 ± 0.03#, £ + 13.92 159.29 ± 16.13### - 81.09 136.76 ± 9.78###, £ - 48.93
  1. UIC Uninfected-untreated mice, IC Infected-untreated mice, PZQ Infected mice treated with praziquantel, SpAE 200 Infected mice treated with Sida pilosa aqueous extract at 200 mg/kg
  2. Data are expressed as mean ± SEM (n = 6). ANOVA followed by Newman-Keuls multiple comparison test was used for statistical analysis. *p < 0.05, **p < 0.01, ***p < 0.001: values are significantly different from those of uninfected-untreated mice (group UIC). #p < 0.05, ###p < 0.001: values are significantly different from those of infected-untreated mice (group IC). £p < 0.05: values are significantly different from those of infected mice treated with praziquantel (group PZQ)