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Table 2 Top pathways associated with down-regulated differentially expressed genes between the EXD group and OVX group

From: The protective effect of Er-Xian decoction against myocardial injury in menopausal rat model

Pathways p Value FDR Genes
Hypertrophic cardiomyopathy 5.47 × 10−5 0.005753 Itgb5, Myh6, Myh7, Myl2, Myl3, Ttn
Dilated cardiomyopathy 6.23 × 10−5 0.005753 Itgb5, Myh6, Myh7, Myl2, Myl3, Ttn
Cardiac muscle contraction 5.01 × 10− 4 0.034695 Myh6, Myh7, Myl2, Myl3, Myl4
Tight junction 7.56 × 10−4 0.041881 Actn2, Ctnna3, Myh13, Myh6, Myh7, Myl2
Arrhythmogenic right ventricular cardiomyopathy 2.70 × 10−3 0.124520 Actn2, Ctnna3, Itgb5, Lef1
Adrenergic signaling in cardiomyocytes 6.10 × 10−3 0.212027 Myh6, Myh7, Myl2, Myl3, Myl4
Viral myocarditis 6.12 × 10−3 0.212027 Myh6, Myh7, RT1-CE7, RT1-T18