Table 2 Top pathways associated with down-regulated differentially expressed genes between the EXD group and OVX group
From: The protective effect of Er-Xian decoction against myocardial injury in menopausal rat model
Pathways | p Value | FDR | Genes |
|---|---|---|---|
Hypertrophic cardiomyopathy | 5.47 × 10−5 | 0.005753 | Itgb5, Myh6, Myh7, Myl2, Myl3, Ttn |
Dilated cardiomyopathy | 6.23 × 10−5 | 0.005753 | Itgb5, Myh6, Myh7, Myl2, Myl3, Ttn |
Cardiac muscle contraction | 5.01 × 10− 4 | 0.034695 | Myh6, Myh7, Myl2, Myl3, Myl4 |
Tight junction | 7.56 × 10−4 | 0.041881 | Actn2, Ctnna3, Myh13, Myh6, Myh7, Myl2 |
Arrhythmogenic right ventricular cardiomyopathy | 2.70 × 10−3 | 0.124520 | Actn2, Ctnna3, Itgb5, Lef1 |
Adrenergic signaling in cardiomyocytes | 6.10 × 10−3 | 0.212027 | Myh6, Myh7, Myl2, Myl3, Myl4 |
Viral myocarditis | 6.12 × 10−3 | 0.212027 | Myh6, Myh7, RT1-CE7, RT1-T18 |