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Table 4 Cytotoxicity assessment on blood lymphocytes by comet parameters

From: Ipomoea batatas L. Lam. ameliorates acute and chronic inflammations by suppressing inflammatory mediators, a comprehensive exploration using in vitro and in vivo models

Sample Comet length(μm) Head length(μm) Tail length(μm) % DNA in head % DNA in tail Tail moment(μm)
IPT-EA 51.56 ± 3.01 44.32 ± 2.56 7.24 ± 0.32b 85.95 ± 3.7ab 14.04 ± 1.48b 0.15 ± 0.03b
IPT-M 56.63 ± 4.21 47.12 ± 1.98 9.51 ± 0.25b 83.20 ± 4.17b 16.79 ± 1.32b 0.21 ± 0.04b
IPR-EA 49.21 ± 3.65 43.21 ± 2.78 5.99 ± 0.22a 87.82 ± 3.52a 12.17 ± 0.89a 0.11 ± 0.02a
IPR-M 53.87 ± 2.89 44.94 ± 2.43 8.93 ± 0.45b 83.42 ± 3.30b 16.57 ± 1.69b 0.18 ± 0.04b
EMS 60.31 ± 3.91 43.12 ± 3.21 17.21 ± 1.5c 71.67 ± 4.31c 28.33 ± 1.91c 1.68 ± 0.32c
Vehicle Control 46.11 ± 3.14 40.32 ± 2.78 5.79 ± 0.34a 88.44 ± 4.67a 11.56 ± 3.01a 0.12 ± 0.02a
  1. IPT-EA, IPT-M, IPR-EA and IPR-M were dosed at 100 μg/ml whereas EMS (Ethyl methane sulfonate) was given in 20 μg/ml concentration. Vehicle = 1% DMSO. Values are expressed as mean ± SD (n = 6). Means with letter “b” indicate significant difference from normal control, “a” and “c” from Ethyl methane sulfonate treated group according to Kruskal-Wallis test at p < 0.05