Ipomoea batatas L. Lam. ameliorates acute and chronic inflammations by suppressing inflammatory mediators, a comprehensive exploration using in vitro and in vivo models

Table 4 Cytotoxicity assessment on blood lymphocytes by comet parameters

Sample	Comet length(μm)	Head length(μm)	Tail length(μm)	% DNA in head	% DNA in tail	Tail moment(μm)
IPT-EA	51.56 ± 3.01	44.32 ± 2.56	7.24 ± 0.32^b	85.95 ± 3.7^ab	14.04 ± 1.48^b	0.15 ± 0.03^b
IPT-M	56.63 ± 4.21	47.12 ± 1.98	9.51 ± 0.25^b	83.20 ± 4.17^b	16.79 ± 1.32^b	0.21 ± 0.04^b
IPR-EA	49.21 ± 3.65	43.21 ± 2.78	5.99 ± 0.22^a	87.82 ± 3.52^a	12.17 ± 0.89^a	0.11 ± 0.02^a
IPR-M	53.87 ± 2.89	44.94 ± 2.43	8.93 ± 0.45^b	83.42 ± 3.30^b	16.57 ± 1.69^b	0.18 ± 0.04^b
EMS	60.31 ± 3.91	43.12 ± 3.21	17.21 ± 1.5^c	71.67 ± 4.31^c	28.33 ± 1.91^c	1.68 ± 0.32^c
Vehicle Control	46.11 ± 3.14	40.32 ± 2.78	5.79 ± 0.34^a	88.44 ± 4.67^a	11.56 ± 3.01^a	0.12 ± 0.02^a

IPT-EA, IPT-M, IPR-EA and IPR-M were dosed at 100 μg/ml whereas EMS (Ethyl methane sulfonate) was given in 20 μg/ml concentration. Vehicle = 1% DMSO. Values are expressed as mean ± SD (n = 6). Means with letter “b” indicate significant difference from normal control, “a” and “c” from Ethyl methane sulfonate treated group according to Kruskal-Wallis test at p < 0.05

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