Hand-foot-mouth disease and use of steroids, intravenous immunoglobulin, and traditional Chinese herbs in a tertiary hospital in Shantou, China

Table 2 Lan-Qin effect on the outcome of HFMD cases ^$

	Total	Recovery^&	Death	Self-discharge	Length of hospital stay (day)
	Total	Recovery^&	Death	Self-discharge	All cases	Without self-discharged cases
Mild cases	1900	1807	0	93	4.09 ± 1.8	4.09 ± 1.7
No Lan-Qin/Other therapies^#	368 (19.4)	348 (19.3)	0 (0)	20 (21.5)	4.03 ± 1.6	4.07 ± 1.5
Lan-Qin only	840 (44.2)	811 (44.9) *	0 (0)	29 (31.2)	3.83 ± 1.5 *	3.89 ± 1.4 *
Lan-Qin + Other therapies	692 (36.4)	648 (35.9)	0 (0)	44 (47.3)	4.43 ± 2.1	4.40 ± 2.0 **
Severe cases	1196	1061	2	133	5.40 ± 3.0	5.47 ± 2.9
No Lan-Qin/Other therapies	47 (3.9)	41 (3.9)	0 (0)	6 (4.5)	4.32 ± 2.1	4.39 ± 2.2
Lan-Qin only	106 (8.9)	97 (9.1)	0 (0)	9 (6.8)	4.25 ± 2.0	4.32 ± 2.0
Lan-Qin + Other therapies	1043 (87.2)	923 (87.0)	2 (100)	118 (88.7)	5.57 ± 3.1 **	5.64 ± 3.0 **
Very severe cases	1	0	1	0	16	16
No Lan-Qin/Other therapies	0 (0)	0 (0)	0 (0)	0 (0)	–	–
Lan-Qin only	0 (0)	0 (0)	0 (0)	0 (0)	–	–
Lan-Qin + Other therapies	1 (100)	0 (0)	1 (100)	0 (0)	16	16
Total	3097	2868	3	226	4.60 ± 2.4	4.60 ± 2.3
No Lan-Qin/Other therapies	415 (13.4)	389 (13.6)	0 (0)	26 (11.5)	4.07 ± 1.6	4.11 ± 1.6
Lan-Qin only	946 (30.5)	908 (31.7)	0 (0)	38 (16.8)	3.88 ± 1.6 *	3.89 ± 1.5
Lan-Qin + Other therapies	1736 (56.1)	1571 (54.8)	3 (100)	162 (71.7)	5.12 ± 2.8 **	5.14 ± 2.7 **

^$Self-discharged cases (n = 302), and the cases treated with steroid only, IVIG only, and steroid/IVIG (n = 602) were excluded from the analysis. ^&Recovery is defined as clearance of fever, erythema, and CNS and cardiopulmonary complications. ^#Lan-Qin was the predominant drug among 8 TCHs prescribed; other therapies include steroids, IVIG, or combination of steroids and IVIG
Data are shown as n (%), or mean ± SD for length of hospital stay. *P < 0.05, **P < 0.01, vs. No Lan-Qin/Other therapies (by χ² test for recovery and t-test for length of hospital stay)

ISSN: 2662-7671