|
Treatment group
|
Spleen index (mean ± SD)
|
Spleen index reduction
|
Log CFU in 0.1 g spleen (mean ± SD)
|
Log reduction
|
|
Non infected
|
0.3 ± 0.2
|
Control
|
–
| |
|
Pretreatment
|
1.09 ± 0.4*
|
↑0.79
|
5.46 ± 0.15
| |
|
Non treatment
|
0.96 ± 0.2*
|
↑0.66
|
4.5 ± 0.1
|
Control
|
|
Doxycycline
|
0.15 ± 0.01*
|
↓0.15
|
2.05 ± 0.07**
|
2.45
|
|
Combination treatment
|
0.19 ± 0.07*
|
↓0.11
|
2.1 ± 0.2**
|
2.4
|
|
C.mongolica root extract
|
0.32 ± 0.05
|
↑0.02
|
3.03 ± 0.15
|
1.47
|
- Statistical analysis: *P < 0.05 and **P < 0.01 comparing the non-infected and non-treatment groups
