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Table 1 Antibacterial efficacies of C. mongolica root extract, antibiotic, and the combination of both treatments in B. melitensis-infected BALB/c mice

From: Anti-Brucella activity of Caryopteris mongolica Bunge root extract against Brucella melitensis infection in mice

Treatment group Spleen index (mean ± SD) Spleen index reduction Log CFU in 0.1 g spleen (mean ± SD) Log reduction
Non infected 0.3 ± 0.2 Control  
Pretreatment 1.09 ± 0.4* ↑0.79 5.46 ± 0.15  
Non treatment 0.96 ± 0.2* ↑0.66 4.5 ± 0.1 Control
Doxycycline 0.15 ± 0.01* ↓0.15 2.05 ± 0.07** 2.45
Combination treatment 0.19 ± 0.07* ↓0.11 2.1 ± 0.2** 2.4
C.mongolica root extract 0.32 ± 0.05 ↑0.02 3.03 ± 0.15 1.47
  1. Statistical analysis: *P < 0.05 and **P < 0.01 comparing the non-infected and non-treatment groups