Skip to main content

Table 2 Effect of H2O2, GFJ, ARI induced alterations alone and in combination, on the levels of enzymatic and non-enzymatic antioxidant contents in serum of control and treated mice

From: Potentiating and synergistic effect of grapefruit juice on the antioxidant and anti-inflammatory activity of aripiprazole against hydrogen peroxide induced oxidative stress in mice

Treatment Groups Group I Control Group II H2O2 Group III GF Group IV ARI Group V GF+ H2O2 Group VI ARI+ H2O2 Group VII ARI + GF + H2O2
ALT (U/ml) 40.07 ± 2.70 103.3 ± 3.40* 36.98 ± 3.30 38.03 ± 3.90 69.42 ± 4.29 *# 49.98 ± 3.43*# 38.99 ± 3.29#
Protein (mg /ml) 4.45 ± 0.90 2.08 ± 0.20* 4.12 ± 0.19 4.57 ± 0.10 3.70 ± 0.70*# 4.38 ± 0.30# 4.98 ± 0.21#
BUN (mg/dl) 43.07 ± 2.69 129.6 ± 4.10* 41.50 ± 3.40 38.06 ± 2.80 73.86 ± 3.67 *# 56.50 ± 2.85*# 40.31 ± 3.28#
Creatinine (mg/dl) 0.32 ± 0.03 0.58 ± 0.07* 0.385 ± 0.06 0.285 ± 0.01 0.48 ± 0.08*# 0.45 ± 0.04*# 0.41 ± 0.06#
CK (U/ml) 66.66 ± 5.30 52.6 ± 7.80* 63.12 ± 5.20 68.28 ± 3.60 69.9 ± 8.70# 71.9 ± 6.30# 60.53 ± 4.9
  1. * Statistically significant when compared to control group (P < 0.0001)
  2. #Statistically significant when compared to H2O2 treated group (P < 0.0001)
  3. Data presented as (mean ± SE) of three independent experiments and No. of animals (n = 10)
\