Table 3 Antimutagenicity testing of the pure compounds against the four S. typhimurium tester strains

L-arginine

5

43.0 ± 0.9^a

22.1 ± 8.4^a

48.6 ± 2.5^a

106.5 ± 1.0^a

2.5

57.1 ± 2.0^b

67.4 ± 3.7^b

96.0 ± 1.1^b

116.1 ± 0.7^a

1

84.1 ± 1.8^b

85.3 ± 3.6^b

124.1 ± 2.4^c

119.3 ± 0.6^a

L-canavanine

5

(−) 101.9 ± 3.7^a

25.1 ± 6.7^a

38.9 ± 1.5^a

101.1 ± 0.7^a

2.5

(−) 120.6 ± 4.5^a

64.8 ± 5.0^b

56.7 ± 2.1^b

116.2 ± 0.4^a

1

(−) 138.2 ± 4.1^a

80.1 ± 2.3^b

92.2 ± 1.7^c

125.9 ± 1.0^a

D-pinitol

5

31.2 ± 8.8^a

26.6 ± 7.3^a

36.1 ± 1.8^a

82.8 ± 3.5^a

2.5

79.0 ± 6.8^b

48.8 ± 6.5^b

79.6 ± 1.8^b

109.5 ± 4.6^a

1

143.5 ± 16.6^c

65.0 ± 10.3^b

117.2 ± 3.0^b

115.0 ± 5.3^a

GABA

5

58.8 ± 3.4^a

14.3 ± 7.9^a

32.9 ± 2.1^a

98.3 ± 1.0^a

2.5

61.8 ± 2.5^a

45.8 ± 5.1^b

66.2 ± 2.5^b

113.1 ± 0.9^a

1

61.4 ± 1.4^a

72.5 ± 3.0^b

105.4 ± 1.5^c

116.7 ± 0.4^a

Positive control

Revertant counts

9-AA

2-AAF

AFB₁

CHP

247 ± 3

358 ± 26

360 ± 3

681 ± 4