Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer’s Disease and Diabetes Mellitus dual therapy

Table 3 Kinetic study of most active fractions BAC, HIC and RMC on AChE, BuChE and α- and β-glucosidase enzyme inhibition

S.No	Plant	Extract	Enzymes	Type of inhibition	Inhibition constant (ki) (μg/mL)
					Ki¹	Ki²
1	B.axillaris	CHCl₃	AChE	Mixed	43.67	61.08
			BuChE	Mixed	56.66	122.3
			α-Glu	Mixed	31.92	81.64
			β-Glu	Mixed	16.03	74.14
2	H.indicus	CHCl₃	AChE	Mixed	19.19	39.68
			BuChE	Mixed	55.69	81.68
			α-Glu	Mixed	66.64	129.01
			β-Glu	Mixed	36.52	51.91
3	R.mysorensis	CHCl₃	AChE	Mixed	71.86	86.31
			BuChE	Mixed	50.11	106.3
			α-Glu	Mixed	38.13	65.92
			β-Glu	Mixed	58.55	99.98

ISSN: 2662-7671