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Table 3 Kinetic study of most active fractions BAC, HIC and RMC on AChE, BuChE and α- and β-glucosidase enzyme inhibition

From: Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer’s Disease and Diabetes Mellitus dual therapy

S.No Plant Extract Enzymes Type of inhibition Inhibition constant (ki) (μg/mL)
      Ki1 Ki2
1 B.axillaris CHCl3 AChE Mixed 43.67 61.08
BuChE Mixed 56.66 122.3
α-Glu Mixed 31.92 81.64
β-Glu Mixed 16.03 74.14
2 H.indicus CHCl3 AChE Mixed 19.19 39.68
BuChE Mixed 55.69 81.68
α-Glu Mixed 66.64 129.01
β-Glu Mixed 36.52 51.91
3 R.mysorensis CHCl3 AChE Mixed 71.86 86.31
BuChE Mixed 50.11 106.3
α-Glu Mixed 38.13 65.92
β-Glu Mixed 58.55 99.98