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Table 2 Effect of DOX and/or AHE treatment on body weight, heart weight and heart /body weight ratio of rats

From: Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats

Treatment (mg/kg) Body weight (BW)(g) Heart weight (HW)(g) Ratio (HW/BWx103)
Initial Final   
Control 219.0 ± 0.577 250.3 ± 0.333b 0.501 ± 0.023 2.00
DOX 221.3 ± 0.667 226.3 ± 0.661a 0.76 ± 0.021a 3.35
AHE alone 220.3 ± 0.667 248.3 ± 0.671b 0.509 ± 0.01b 2.04
DOX + AHE (200) 221.7 ± 0.882 232.2 ± 0.611a,b 0.651 ± 0.019a**b*c** 2.80
DOX + AHE (400) 220.3 ± 0.882 244.7 ± 0.882a,b,c 0.534 ± 0.017b 2.18
DOX + Sily 222.0 ± 0.577 243.3 ± 0.333a,b 0.541 ± 0.018b 2.22
  1. Data expressed as mean ± SEM (n = 6)
  2. asignificant difference of final body weight of group Vs. Control group at p < 0.0001
  3. bsignificant difference of final body weight of group Vs. DOX-treated group at p < 0.0001
  4. csignificant difference of final body weight of DOX + AHE (200 mg/kg) treated group Vs. DOX + AHE (400 mg/kg) treated group at p < 0.001
  5. *, **indicate significance at p < 0.05 and p < 0.001. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters. (One way ANOVA followed by Tukey’s multiple comparison tests). Sily-Silymarin
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