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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats

Fig. 2

Histopathological changes induced by Doxorubicin and protective effect of AHE in rat heart (H&E staining, magnification 40X). Group 1: Cardiac section from control rats showing normal morphology. Group 2: cardiac sections from DOX-treated rats reveal degenerative changes. Group 3: Represents cardiac section from AHE alone treated rats. Group 4: AHE (200 mg/kg b.w) showed reduced degenerations. Group 5: AHE (400 mg/kg b.w) results in significant protection against DOX induced cardiac injury. Group 6: Showed protective effect of Silymarin treatment. AHE: A.hydaspica ethyl acetate fraction, DOX: Doxorubicin, H: hypertrophy, N: necrosis, CI: cellular infiltrations

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