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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Assessing the recovery from prerenal and renal acute kidney injury after treatment with single herbal medicine via activity of the biomarkers HMGB1, NGAL and KIM-1 in kidney proximal tubular cells treated by cisplatin with different doses and exposure times

Fig. 2

Herbal medicines regulated NGAL and KIM-1 biomarkers. Pretreatment with NAC 10 mM for 1 h and stimulated with cisplatin (10 μM) for 24 h (a). Cytotoxicity was measured by MTT assay treatment with herbal medicine and cisplatin for 24 h (b). NGAL and KIM-1 were measured by ELISA (c and d). Lane 1:; Artemisia capillaris, Lane 2:; Houttuynia cordata, Lane 3:; Leonurus japonicas, Lane 4:; Nelumbo nymphaea, Lane 5:; Schisandra chinensis, Lane 6:; Akebia quinata, Lane 7:; Ligustrum japonicus, Lane 8:; Paeonia suffruticosa, Lane 9:; Phellodendron amurense, Lane 10:; Trichosanthes kirilowii. The statistical significance (*p < 0.05) of the observed differences between cisplatin treated and cisplatin + NAC groups were statistically tested by t-test

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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