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Table 3 MMSE change among AD patients with different severities

From: Adding Chinese herbal medicine to conventional therapy brings cognitive benefits to patients with Alzheimer’s disease: a retrospective analysis

 

MMSE change

6 m

12 m

18 m

24 m

Mild (MMSE 21–26)

 CT + H

mean ± SE

0.03 ± 0.42

−0.15 ± 0.47

−1.21 ± 0.40

−0.06 ± 0.48

95% CI

−0.83 to 0.88

−1.12 to 0.81

−2.09 to −0.33

−1.1 to 0.97

N

36

32

14

15

 CT

mean ± SE

−0.16 ± 0.75

0.13 ± 0.83

−2.66 ± 0.77

−2.66 ± 0.73

95% CI

−1.75 to 1.41

−1.66 to 1.93

−4.36 to −0.96

−4.27 to −1.05

N

18

15

11

12

P value

0.043

0.660

0.030

0.012

Moderate (MMSE 10–20)

 CT + H

mean ± SE

1.5 ± 0.63

0.46 ± 0.91

−1.9 ± 0.7

−2.84 ± 0.61

95% CI

0.21 to 2.78

−1.49 to 2.42

−3.49 to −0.3

−4.19 to −1.49

N

28

15

10

13

 CT

mean ± SE

1.14 ± 0.68

−2.38 ± 0.67

−3.6 ± 0.42

−5 ± 0.34

95% CI

−0.34 to 2.62

−3.85 to −0.91

−4.5 to −2.69

−5.75 to −4.24

N

14

13

15

14

P value

0.196

0.001

0.253

0.025

  1. As severe cases were few, the analysis were done only in mild and moderate AD patients. Differences between CT + H and CT were observed at 12 to 24 months in moderate group, but later at 24 months in mild group. MMSE denotes mini-mental state examination; CT + H denotes conventional therapy with herbal medicine; CT denotes conventional therapy alone
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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