Table 1 Top 10 differentially expressed genes at 24 h and 48 h treatment
Upregulation | Downregulation | ||||||
|---|---|---|---|---|---|---|---|
24 h | 48 h | 24 h | 48 h | ||||
Gene | Fold change | Gene | Fold change | Gene | Fold change | Gene | Fold change |
AKR1C4 | 11.81 ± 0.28 | FAM129A | 18.46 ± 0.25 | TXNIP | −4.17 ± 0.65 | TXNIP | −12.75 ± 0.43 |
AKR1C3 | 9.15 ± 0.18 | GDF15 | 15.70 ± 0.27 | GPER | −3.10 ± 0.25 | AFAP1L2 | −5.26 ± 0.32 |
AKR1C2 | 7.44 ± 0.21 | DDIT3 | 14.73 ± 0.32 | KCNK12 | −2.79 ± 0.78 | ID3 | −4.52 ± 0.38 |
FGB | 5.72 ± 0.73 | FLJ35767 | 14.48 ± 0.22 | AFAP1L2 | −2.56 ± 0.34 | EFEMP1 | −4.27 ± 0.38 |
CYP1A1 | 5.30 ± 0.22 | HSPA6 | 14.23 ± 0.49 | SAMD11 | −2.45 ± 0.24 | NUDT1 | −4.21 ± 0.18 |
GDF15 | 4.50 ± 0.20 | LCN2 | 12.99 ± 0.27 | KCNJ8 | −2.39 ± 0.23 | ID1 | −4.05 ± 0.51 |
FGG | 4.43 ± 0.48 | AKR1C3 | 12.88 ± 0.31 | EFEMP1 | −2.29 ± 0.29 | CCL2 | −4.02 ± 0.38 |
ADM | 4.18 ± 0.50 | AKR1C4 | 11.33 ± 0.30 | ID1 | −2.12 ± 0.75 | GPER | −3.99 ± 0.20 |
RASD1 | 4.15 ± 0.78 | CYP1A1 | 11.27 ± 0.23 | SMAD7 | −2.02 ± 0.13 | ELOVL2 | −3.91 ± 0.19 |
ABCC3 | 4.11 ± 0.44 | F7 | 10.84 ± 0.20 | ID3 | −2.00 ± 0.50 | KCNJ8 | −3.88 ± 0.19 |