Table 3 Antiproliferative activity of fractions of M. barteri and C. portoricensis
Plant | Fractions | Antiproliferative activity CC50 (μg/mL) |  | Selectivity Index |  | |
|---|---|---|---|---|---|---|
RD | Vero | PNT2 | Vero | PNT2 | ||
M. barteri | hexane | 25.6 ± 0.21 | 62.07 ± 0.98 | 88.23 ± 2.11 | 2.4 | 3.4 |
DCM | 0.15 ± 0.01 | 2.06 ± 0.11 | 2.91 ± 0.18 | 13.7 | 19.4 | |
EtOAc | 2.98 ± 0.09 | 10.87 ± 0.35 | 17.12 ± 0.41 | 3.7 | 5.7 | |
aqueous | 3.06 ± 0.11 | 13.04 ± 0.41 | 18.13 ± 1.03 | 4.3 | 5.9 | |
C. portoricensis | hexane | 2.99 ± 0.04 | ND | 15.11 ± 1.02 | – | 5.1 |
EtOAc | 0.25 ± 0.03 | ND | 2.77 ± 0.12 | – | 11.1 | |
aqueous | 3.04 ± 0.19 | ND | 12.12 ± 0.67 | – | 4.0 | |
Cyclophosphamide | CTX | 0.97 ± 0.03 | 5.23 ± 0.21 | ND | – | 5.4 |