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Table 5 Effects of the chloroform and methanol fractions of Moringa stenopetala on carrageenan- induced paw edema and percent inhibition from increase in paw volume

From: Anti-inflammatory and analgesic activities of solvent fractions of the leaves of Moringa stenopetala Bak. (Moringaceae) in mice models

 

Change in paw volume (ml) and percent inhibition (%)

Group

0 h

1 h

%

2 h

%

3 h

%

4 h

%

5 h

%

TE

0.43 ± 0.01

0.57 ± 0.01

0.73 ± 0.01

0.76 ± 0.01

0.81 ± 0.02

0.88 ± 0.04

ASA

0.42 ± 0.01

0.51 ± 0.02a3c1d1

36.1

0.53 ± 0.01a3c3d3g3

63.9

0.58 ± 0.02a3c3d3h1

50.8

0.64 ± 0.01a3c3d3g3

42.6

0.67 ± 0.01a3c3d3g3

45.3

CF 100

0.43 ± 0.01

0.57 ± 0.01

4.5

0.68 ± 0.01

15.1

0.72 ± 0.03

11.4

0.79 ± 0.01

4.8

0.85 ± 0.01

6.3

CF 200

0.44 ± 0.01

0.56 ± 0.01

7.7

0.67 ± 0.01

18.2

0.72 ± 0.02

12.9

0.78 ± 0.02

9.5

0.85 ± 0.01

9.2

CF 400

0.45 ± 0.01

0.58 ± 0.01

2.3

0.67 ± 0.01a1h3

24.4

0.70 ± 0.01a1h1

22.8

0.76 ± 0.01a2f1h3

18.0

0.80 ± 0.01a3h3

20.8

MF 100

0.42 ± 0.01

0.54 ± 0.01

11.3

0.63 ± 0.02a3h1

26.8

0.67 ± 0.01a3b3

24.0

0.71 ± 0.01a3h1

22.8

0.76 ± 0.01a3h2

23.4

MF 200

0.45 ± 0.01

0.57 ± 0.01

3.8

0.64 ± 0.01a3h2

33.0

0.69 ± 0.01a2b3

25.2

0.73 ± 0.01a3h2

25.4

0.78 ± 0.01a3h3

26.3

MF 400

0.44 ± 0.01

0.54 ± 0.02

21.8

0.58 ± 0.01a3

52.2

0.64 ± 0.02a3b1

37.2

0.68 ± 0.03a3e3

36.8

0.71 ± 0.01a3

39.7

  1. Values are expressed as Mean ± S.E.M (n = 6); aagainst the control, bagainst the standard drug, cagainst CF100, dagainst CF200, eagainst CF400, fagainst MF 100, gagainst MF 200, hagainst MF 400. 1 P < 0.05, 2 P < 0.01, 3 P < 0.001; TE tween 80, ASA: aspirin, CF and MF refers to chloroform and methanol fractions of Moringa stenopetala respectively; control received 2% Tween 80, 10 ml/kg, whereas:ASA, standard received Aspirin 100 mg/kg orally; Numbers refer to dose in mg/kg