Table 8 Clinical chemistry data for male rats treated with JDHY granules for 13 weeks
From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats
Dose (g/kg/d) | 0 | 80 | 100 | 130 |
|---|---|---|---|---|
Males | ||||
AST(U/L) | 217.31 ± 45.65 | 220.68 ± 66.49 | 219.30 ± 86.66 | 196.71 ± 77.69 |
ALT(U/L) | 61.57 ± 9.09a | 61.62 ± 10.59 | 56.86 ± 10.71 | 58.01 ± 12.24 |
ALP(U/L) | 221.68 ± 88.98 | 239.23 ± 64.49 | 242.42 ± 81.93 | 266.23 ± 82.01 |
TP(g/L) | 85.04 ± 4.67 | 82.7 ± 06.51 | 80.61 ± 6.84 | 86.03 ± 5.78 |
ALB(g/L) | 42.04 ± 4.63 | 41.80 ± 4.78 | 40.84 ± 5.50 | 38.76 ± 5.31 |
TBIL(umol/L) | 7.98 ± 2.34 | 8.30 ± 2.54 | 7.91 ± 2.30 | 7.86 ± 3.32 |
CHOL(mmol/L) | 1.42 ± 0.45 | 1.64 ± 0.49 | 1.44 ± 0.46 | 1.53 ± 0.33 |
TG(mmol/L) | 0.33 ± 0.11 | 0.35 ± 0.11 | 0.36 ± 0.08 | 0.38 ± 0.08 |
GLU(mmol/L) | 7.06 ± 0.97 | 7.43 ± 0.74 | 7.33 ± 0.71 | 7.65 ± 0.91 |
BUN(mmol/L) | 6.80 ± 1.11 | 6.78 ± 1.64 | 6.46 ± 1.41 | 6.47 ± 1.61 |
Cr(umol/L) | 97.32 ± 15.24 | 97.65 ± 15.57 | 99.23 ± 15.67 | 98.54 ± 13.81 |
CK(U/L) | 155.05 ± 25.48 | 147.16 ± 23.52 | 153.79 ± 26.00 | 150.48 ± 24.85 |
Na+(mmol/L) | 150.29 ± 17.72 | 143.53 ± 15.43 | 141.36 ± 18.28 | 145.52 ± 21.69 |
K+(mmol/L) | 4.59 ± 0.93 | 5.07 ± 1.31 | 4.96 ± 1.07 | 5.01 ± 0.84 |
Cl−(mmol/) | 110.30 ± 6.30 | 105.50 ± 7.89 | 105.40 ± 6.93 | 108.00 ± 7.07 |