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Table 2 Integrated optical densities of the immunohistochemical staining for IL-1β and TNF-α

From: Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production

  Controls P. gingivalis Nal-P-113 (n = 12)
(n = 12) (n = 12) 6.25 μg/mL 25 μg/mL 100 μg/mL 400 μg/mL
IL-1β 5.32 ± 0.93 54.26 ± 2.94 49.32 ± 9.81 40.50 ± 5.61 19.78 ± 3.40a 12.40 ± 2.51a
TNF-α 4.63 ± 0.57 27.11 ± 1.60 24.63 ± 5.17 20.94 ± 3.77 12.62 ± 2.67a 9.09 ± 2.07a
  1. a P < 0.05, compared with the P. gingivalis group