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Table 3 Effect of ethanolic extract of E. hirta whole plant on excision wound in alloxan induced diabetic rats

From: Wound healing effect of Euphorbia hirta linn. (Euphorbiaceae) in alloxan induced diabetic rats

Group/
Post wounding days
Wound area (cm2) % of wound contraction at the end of the study
1st day 4th day 8th day 12th day 16th day  
Group I N/A N/A N/A N/A N/A N/A
Group II 4.90 ± 1.13 4. 90 ± 1.20 4.85 ± 0.88 4.72 ± 0.89 4.60 ± 0.93 6.12
Group III 4.90 ± 1.11 4.83 ± 1.05 4.58 ± 1.17 3.76 ± 0.59 3.14 ± 0.36 35.92
Group IV 4.90 ± 1.03 4.70 ± 0.91 4.50 ± 0.86 3.23 ± 0.65 2.71 ± 0.40* 44.69
Group V 4.90 ± 1.10 4.58 ± 1.07 4.16 ± 0.88 2.48 ± 0.33* 1.89 ± 0.35** 61.42
Group VI 4.90 ± 1.12 4.51 ± 1.01 4.35 ± 0.76 3.26 ± 0.33 2.95 ± 0.54* 39.79
Group VII 4.90 ± 1.16 4.83 ± 1.21 4.55 ± 0.73 3.92 ± 0.58 3.29 ± 0.37 32.86
Group VIII 4.90 ± 0.88 4.75 ± 1.03 4.47 ± 0.68 3.41 ± 0.56 3.12 ± 0.49 36.32
  1. Each value is Mean ± S.E.M (n = 3). (*) indicates statistically significant difference from the diabetic wound control using ANOVA, followed by Dunnett’s multiple comparison test (** p < 0.01). (†) indicates statistically no significant difference from the diabetic wound control using ANOVA, followed by Dunnett’s multiple comparison test (p > 0.05). Group I = normal control, Group II = Diabetic wound control, Group III = Diabetic wound control +100 mg ethanolic extract of E. hirta, Group IV = Diabetic wound control +200 mg ethanolic extract of E. hirta, Group V = Diabetic wound control +400 mg ethanolic extract of E. hirta, Group VI = Diabetic wound control +5% Povidone iodine, Group VII = Diabetic wound control +5% ethanolic extract of E. hirta, Group VIII = Diabetic wound control +10% ethanolic extract of E. hirta