Table 2 LC50 of L. lanceolata crude extracts and positive control tested against C. elegans wild type and ivermectin-, levamisole- and albendazole mutant resistant strains of the free living nematode C. elegans after 48 h and 72 h post-treatment. Data are mean ± SEM from three independent duplicate experiments

C. elegans

Leaves

Trunk barks

Root barks

Leaves

Trunk barks

Root barks

Ivermectin

Levamisole

Albendazole

Wild type

4650.00 ± 1.58 ^**

(8210.00 ± 2.71)^***

1200.00 ± 0.47 ^ns

(2370.00 ± 0.66)^**

1890.00 ± 0.26 ^**

(3030.00 ± 0.92)^***

3530.00 ± 0.78 ^***

(5440.00 ± 1.45^***)

2030.00 ± 0.36 ^** (2070.00 ± 0.39^**)

1000.00 ± 0.33 ^ns

(2640.00 ± 0.52^*)

2.17 ± 0.66 ^**

(2.41 ± 0.33)^***

4.12 ± 0.31 ^**

(4.15 ± 0.68)^**

4.26 ± 0.01 ^**

(4.35 ± 0.57)^***

CB3474

1030.00 ± 3.07***

(1039.00 ± 1.65) ^ns

2810.00 ± 0.10 ^ns

(4267.00 ± 0.02) ^***

2030.00 ± 0.35 ^ns

(2803 ± 0,16) ^ns

1470.00 ± 0.3 ^***

(2830.00 ± 1.37 ^ns)

2620.00 ± 0.22 ^ns

(3070.00 ± 0.34 ^***)

1860.00 ± 0.20 ^ns

(2680.00 ± 0.25 ^ns)

-

-

> 100

CB211

4220.00 ± 0.55**

(7580.00 ± 2.38) ^ns

4720.00 ± 2.11 ^ns

(1162.00 ± 3.49) ^***

2270.00 ± 0.66 ^ns

(3063.00 ± 0.88) ^ns

3750.00 ± 0.32 ^ns

(5510.00 ± 1.37^*)

3670.00 ± 0.75 ^ns

(8790.00 ± 0.29^***)

2200.00 ± 0.36 ^ns

(2940.00 ± 0.62 ^ns)

-

> 100

-

VC722

1170.00 ± 0.60***

(5210.00 ± 2.61) ^ns

4120.00 ± 0.73 ^ns

(7937.00 ± 1.65) ^ns

2850.00 ± 0.35 ^ns

(5260.00 ± 5.10) ^ns

1820.00 ± 0.90 ^ns

(5870.00 ± 1.47^ns)

3970.00 ± 0.55 ^ns

(6920.00 ± 1.33^**)

2500.00 ± 0.37 ^ns

(2620.00 ± 0.37 ^ns)

> 100

-

-