Fig. 2

Frequency of rearing (A and B) and line-crossings (C and D) of mice treated with chlorpromazine (CPZ; 1 mg/kg, i.p), SNE and vehicle (Veh) when observed for 5 min in an open-field paradigm. Data are mean ± SEM (n = 5). *P ≤ 0.05, ** P ≤ 0.01, ***P ≤ 0.001 compared with vehicle group (one-way ANOVA followed by a Dunnett’s multiple comparison post hoc test)