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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Effects of the combined extracts of Herba Epimedii and Fructus Ligustrilucidi on airway remodeling in the asthmatic rats with the treatment of budesonide

Fig. 5

Effects of budesonide and the herbal extracts on mRNA expression of TGF-β/Smads. The mRNA expressions of TGF-β1 (a), TGF-β2 (b), Smad2 (c), Smad3 (d) and Smad7 (e) in lung tissue were determined by qPCR with β-actin as an internal control. In the asthmatic rats, the mRNA expressions of TGF-β1, TGF-β2, Smad2 and Smad3 were significantly higher, while that of Smad7 was significantly lower than those in the normal group. Mean ± SD, n = 7. * P < 0.05 and ** P < 0.01 compared to normal control group; # P < 0.05 and ## P < 0.01 compared to asthma model group; ▲ P < 0.05 and ▲▲ P < 0.01 compared to budesonide group; ● P < 0.05 compared to extracts group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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