Metabolite
|
LPS alone
|
LPS + RES (25 μM)
|
p
|
---|
PGE2 [pg/mL] | 6334 ± 306 | 2816 ± 134 | 0.010 |
Nitric oxide (μM) | 20.1 ± 0.8 | 12.1 ± 0.4 | 0.005 |
- Cells were incubated with 25 μM RES, stimulated with 1 μg/mL LPS and cultured for 24 h. ‘LPS alone’: indicates the value obtained from LPS-stimulated cells (without RES). Results are shown as mean (± SEM) of triplicate cultures obtained in 5 independent experimental series. p values were calculated between treatments ‘LPS-alone’ versus ‘LPS + RES’. Unstimulated cells produced metabolites at <10% of LPS-stimulated cells