Fig. 4

The effects of sesamin on GAGs production in IL-1β 3-day pre-treated HAC pellets. a Effects of sesamin on GAGs secretion to the culture medium over 21 days; b GAGs accumulation in the pellet matrix after 21 days treatment; and c total GAGs production after 21 days treatment. Data presented are the mean ± S.D. of three independent cultures. Statistical significance of the difference between IL-1β pre-treatment alone and untreated (control): # = p < 0.05; between sesamin treatment and IL-1β pre-treatment alone: * = p < 0.05