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Table 4 Anti-inflammatory activity of Prunus domestica gum-loaded gold nanoparticles

From: A multi-target therapeutic potential of Prunus domestica gum stabilized nanoparticles exhibited prospective anticancer, antibacterial, urease-inhibition, anti-inflammatory and analgesic properties.

Treatment 1st h 2nd h 3rd h 4th h 5th h
Group 1 Saline 0.247 ± 0.026 0.250 ± 0.022 0.265 ± 0.013 0.250 ± 0.014 0.250 ± 0.016
Group 2 Carrageenan 0.355 ± 0.013### 0.370 ± 0.026### 0.385 ± 0.021### 0.397 ± 0.026### 0.405 ± 0.013###
Group 3 Diclofenac (50 mg/kg) 0.287 ± 0.029** 0.265 ± 0.019*** 0.265 ± 0.031*** 0.287 ± 0.025*** 0.305 ± 0.012***
Group 4 Gum (200 mg/kg) 0.302 ± 0.009* 0.290 ± 0.008*** 0.295 ± 0.013*** 0.305 ± 0.013*** 0.315 ± 0.019***
Group 5 Gum (400 mg/kg) 0.282 ± 0.017*** 0.292 ± 0.012*** 0.287 ± 0.012*** 0.280 ± 0.022*** 0.290 ± 0.018***
Group 6 Gold nanoparticles (40 mg/kg) 0.305 ± 0.021* 0.307 ± 0.012*** 0.305 ± 0.012*** 0.302 ± 0.015*** 0.317 ± 0.026***
Group 7 Gold nanoparticles (80 mg/kg) 0.295 ± 0.013** 0.287 ± 0.017*** 0.295 ± 0.013*** 0.287 ± 0.022*** 0.300 ± 0.018***
  1. Values expressed as mean paw volume in mL ± SD. ### P <0.001 compared to group 1. * P <0.05, ** P <0.01, *** P <0.001 compared to group 2. One-way ANOVA followed by Tukey’s post hoc test. Results are the means of 6 animals per group