Groups | Dose, mg/kg | AST, U/L | ALT, U/L | Urea, mg/dL | Creatinine, mg/dL |
---|---|---|---|---|---|
Healthy animals | - | 283.2 ± 24.9 | 53.6 ± 6.55 | 39.0 ± 1.9 | 0.4 ± 0.0 |
Tumor control | - | 242.0 ± 12.2 | 67,80 ± 7,11 | 43.0 ± 7.1 | 0.3 ± 0.0 |
5-FU | 25 | 199.3 ± 38.4 | 39.00 ± 9.51 | 33.2 ± 1.5 | 0.51 ± 0.02 |
EOM | 50 | 217.4 ± 27.4 | 53.8 ± 11,81 | 27.5 ± 12.0 | 0.2 ± 0.0 |
EOM | 100 | 285.4 ± 22.1 | 60.3 ± 1.43 | 45.9 ± 5.7 | 0.2 ± 0.0 |
EOM | 150 | 320.2 ± 73.9 | 44.0 ± 6.86 | 81.8 ± 8.4a,b | 0.6 ± 0.2 |
Fenchone | 30 | 155.8 ± 7.5a,b | 29,25 ± 2,68a | 38.8 ± 3.8 | 0.3 ± 0.0 |
Fenchone | 60 | 163.8 ± 8.5a,b | 34.6 ± 5.4a | 37.8 ± 2.4 | 0.2 ± 0.0 |