Skip to main content

Table 5 Feed and water consumption and weight of animals (n = 6) subjected to different treatments (9 days)

From: Toxicity and antitumor potential of Mesosphaerum sidifolium (Lamiaceae) oil and fenchone, its major component

Groups Dose, mg/kg Water consumption, ml Feed consumption, g Gain/loss of weight, %
Healthy animals - 35.6 ± 1.1 30.9 ± 1.6 12.79 ± 3.0
Tumor control - 34.6 ± 2.1 29.3 ± 1.5 11.3 ± 1.1
5-FU 25 29.4 ± 1.8 32.8 ± 1.2 −10.1 ± 1.2a,b
EOM 50 47.2 ± 2.3a,b 33.9 ± 2.9 17.3 ± 4.7c
EOM 100 32.5 ± 1.6 30.8 ± 1.6 −8.6 ± 4.3a,b
EOM 150 29.4 ± 2.7 23.3 ± 2.1a −12.9 ± 1.9 a,b
Fenchone 30 42.2 ± 1.0a,b,c 35.6 ± 0.8 5.6 ± 0.9c
Fenchone 60 46.6 ± 1.6a,b,c 35.3 ± 0.1 10.23 ± 3.4c
  1. Data presented as mean ± SEM of six animals analyzed by ANOVA followed by Tukey test. a p < 0.05 compared to tumor control. b p<0.05 compared to healthy animals. c p<0,05 compared to 25 mg/kg 5-FU group by ANOVA followed by Tukey