Edema (10–2/mL) (mean ± SD) | Edema inhibition (%) | |||||||
---|---|---|---|---|---|---|---|---|
Treatment | Dose (mg/kg) | 1 h | 3 h | 5 h | 1 h | 3 h | 5 h | |
Control | 34 ± 1,5 | 59,5 ± 1,7 | 68,3 ± 1,09 | |||||
KS | Methanol extract | 100 | 27,03 ± 1,9 | 29,26 ± 1,1* | 35,01 ± 0,89* | 20,5 | 50,82 | 48,74 |
200 | 23,08 ± 2,8* | 24,11 ± 0,8* | 30,13 ± 1,04* | 32,11 | 59,47 | 55,88 | ||
300 | 19,1 ± 1,5** | 23,34 ± 1,8** | 28,04 ± 1,65* | 43,82 | 60,77 | 58,94 | ||
Aquous extract | 100 | 25,5 ± 1,07 | 27,12 ± 2,02* | 33,37 ± 1,98* | 25 | 54,42 | 51,14 | |
200 | 20,17 ± 2,3* | 22,02 ± 1,98** | 27,52 ± 2,67* | 40,67 | 62,99 | 59,70 | ||
300 | 17 ± 2,7** | 19,69 ± 1,08** | 24,6 ± 2,13* | 50 | 66,90 | 63,98 | ||
Acetone extract 80% | 100 | 29,24 ± 2,1 | 35,17 ± 2,09* | 38,14 ± 2,87* | 14 | 40,89 | 44,15 | |
200 | 26,18 ± 1,03 | 29,04 ± 1,98* | 34,21 ± 1,89* | 23 | 51,19 | 49,91 | ||
300 | 21,41 ± 1,75* | 26,3 ± 1,91* | 32,12 ± 2,09* | 37,02 | 55,79 | 52,97 | ||
Acetone extract 100% | 100 | 30,09 ± 0,89 | 37,15 ± 2,09 | 41,07 ± 2,01* | 11,5 | 37,56 | 39,86 | |
200 | 27,23 ± 2,87 | 32,21 ± 2,02* | 39,51 ± 1,09* | 19,91 | 45,86 | 42,15 | ||
300 | 23,35 ± 1,98* | 27,5 ± 1,89* | 34,21 ± 1,19* | 31,32 | 53,78 | 49,91 | ||
AS | Methanol extract | 100 | 27,5 ± 1,76 | 31,15 ± 1,09* | 36,29 ± 1,2* | 19,11 | 47,64 | 46,86 |
200 | 24,41 ± 1,57 | 27,21 ± 2,08* | 32,14 ± 1,14* | 28,20 | 54,26 | 52,94 | ||
300 | 20,06 ± 1,4* | 24,5 ± 2** | 30,34 ± 2,03* | 41 | 58,82 | 55,57 | ||
Aquous extract | 100 | 26,18 ± 2,34 | 28,41 ± 2,02 | 34,21 ± 3,01* | 23 | 52,25 | 49,91 | |
200 | 21,5 ± 2,04* | 23,34 ± 1,03* | 29,02 ± 1,2* | 36,76 | 60,77 | 57,51 | ||
300 | 18,05 ± 2,01** | 21,7 ± 1,65* | 27 ± 2,98* | 46,91 | 63,52 | 60,46 | ||
Acetone extract 80% | 100 | 28,5 ± 1,87 | 35,17 ± 1,05 | 38,04 ± 2,07* | 16,17 | 40,89 | 44,30 | |
200 | 26,18 ± 1,94 | 31,97 ± 2,3 | 35,15 ± 1,84* | 23 | 46,26 | 48,53 | ||
300 | 23,12 ± 1,87* | 28,41 ± 2,03 | 34,21 ± 1,90* | 32 | 52,25 | 49,91 | ||
Acetone extract 100% | 100 | 30,83 ± 1,02 | 38,38 ± 1,98 | 45,24 ± 2,03* | 9,32 | 35,49 | 33,76 | |
200 | 29,7 ± 1,09 | 34,29 ± 1,25 | 41,17 ± 2,5* | 12,64 | 42,36 | 39,72 | ||
300 | 25,47 ± 2,01 | 28,17 ± 1,38 | 35,05 ± 1,76* | 25,08 | 52,65 | 48,68 | ||
Asl | 300 | 22,29 ± 1,09* | 25,33 ± 1,34 | 31,61 ± 1,87 | 34,44 | 57,42 | 53,71 |